Borussertib [1800070-77-2]

MedChem Express

Borussertib [1800070-77-2]

10

1800070-77-2

Research Use Only

99.18

C36H32N6O3

596.68

Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt[1].

C=CC(NC1=CC=C(N2)C(N(C3CCN(CC4=CC=C(C5=NC6=C(C(NC=C6)=O)C=C5C7=CC=CC=C7)C=C4)CC3)C2=O)=C1)=O

-20°C,2°C to 8°C

12352200