Borussertib [1800070-77-2]

TargetMol Chemicals

Borussertib [1800070-77-2]

9

1800070-77-2

Research Use Only

Borussertib

98.18%

C36H32N6O3

596.68

Borussertib is a first-in-class covalent-allosteric inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt.

3 years

C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(cc4)-c4nc5cc[nH]c(=O)c5cc4-c4ccccc4)CC3)c2c1

-20°C

12352200