Borussertib

AbMole BioScience

Borussertib

9

1800070-77-2

Research Use Only

C36H32N6O3

596.68

Borussertib is a first-in-class covalently-mutated inhibitor of the protein kinase Akt, with an IC50 value of 0.8 nM and a Ki value of 2.2 nM for Aktwt.

C=CC(=O)NC1=CC2=C(NC(=O)N2C3CCN(CC3)CC4=CC=C(C=C4)C5=NC6=C(C=C5C7=CC=CC=C7)C(=O)NC=C6)C=C1

12352200