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BT2 [34576-94-8]

BT2 [34576-94-8]

T14834
TargetMol Chemicals
CAS Number34576-94-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.77%
Molecular Weight247.1
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    BT2 [34576-94-8]
  • Delivery Days Customer
    4
  • CAS Number
    34576-94-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    BT2
  • Estimated Purity
    99.77%
  • Molecular Formula
    C9H4Cl2O2S
  • Molecular Weight
    247.1
  • Scientific Description
    BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 microM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 microM. Its interaction with BDK induces helix movements in the N-terminal domain, leading to BDKs dissociation from the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC).
  • Shelf life instruction
    3 years
  • SMILES
    OC(=O)c1sc2cc(Cl)ccc2c1Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200