BT2

AbMole BioScience

BT2

9

34576-94-8

Chemical

Research Use Only

C9H4Cl2O2S

247.1

BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 uM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain alfa-ketoacid dehydrogenase complex (BCKDC). BT2 is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 uM.

OC(=O)C1=C(Cl)C2=CC=C(Cl)C=C2S1

Powder -20°C

12352200