c-Myb(MYB286), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040286
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetMYB
Overview
- SupplierBiotium
- Product Namec-Myb(MYB286), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMYB286
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID4602
- Target nameMYB
- Target descriptionMYB proto-oncogene, transcription factor
- Target synonymsCmyb; c-myb; c-myb_CDS; efg; oncogene AMV; proto-oncogene c-Myb; transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog
- HostMouse
- IsotypeIgG1
- Protein IDP01104
- Protein NameTransforming protein Myb
- Scientific DescriptionThe highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203