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ProductsBack/c-Myc antibody [JAC6]

c-Myc antibody [JAC6]

Research Use Only
GTX10910
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Plant
TargetMYC
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Overview

  • Supplier
    GeneTex
  • Product Name
    c-Myc antibody [JAC6]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes the sequence EQKLISEEDL.
  • Application Supplier Note
    WB: 1/500-1/1,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    JAC6
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID4609
  • Target name
    MYC
  • Target description
    MYC proto-oncogene, bHLH transcription factor
  • Target synonyms
    avian myelocytomatosis viral oncogene homolog; bHLHe39; class E basic helix-loop-helix protein 39; c-Myc; MRTL; myc proto-oncogene protein; MYCC; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
  • Host
    Rat
  • Isotype
    IgG1
  • Protein IDP01106
  • Protein Name
    Myc proto-oncogene protein
  • Scientific Description
    This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
  • Reactivity
    Human, Plant
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Atrophy of White Adipose Tissue Accompanied with Decreased Insulin-Stimulated Glucose Uptake in Mice Lacking the Small GTPase Rac1 Specifically in Adipocytes. Hasegawa K et al., 2021 Oct 5, Int J Mol Sci
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  • A Crucial Role for the Small GTPase Rac1 Downstream of the Protein Kinase Akt2 in Insulin Signaling that Regulates Glucose Uptake in Mouse Adipocytes. Takenaka N et al., 2019 Oct 31, Int J Mol Sci
    Read more
  • The powdery mildew resistance gene Pm8 derived from rye is suppressed by its wheat ortholog Pm3. Hurni S et al., 2014 Sep, Plant J
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  • The nucleolus exhibits an osmotically regulated gatekeeping activity that controls the spatial dynamics and functions of nucleolin. Yang L et al., 2008 Apr 25, J Biol Chem
    Read more