IHC-P analysis of human pancreas tissue using GTX27761 C-Peptide antibody [C-PEP-01].
IHC-P analysis of human pancreas tissue using GTX27761 C-Peptide antibody [C-PEP-01].
C-Peptide antibody [C-PEP-01]
GTX27761
ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, RadioImmunoAssay
Product group Antibodies
ReactivityHuman
TargetINS
Overview
- SupplierGeneTex
- Product NameC-Peptide antibody [C-PEP-01]
- Delivery Days Customer9
- Antibody SpecificityThis antibody reacts specifically with C-peptide, No cross-reactivity with Insulin or other peptide hormones or proteins was observed.
- ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, RadioImmunoAssay
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDc-pep-01
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3630
- Target nameINS
- Target descriptioninsulin
- Target synonymsIDDM; IDDM1; IDDM2; ILPR; insulin; IRDN; MODY10; PNDM4; preproinsulin; proinsulin
- HostMouse
- IsotypeIgG1
- Scientific DescriptionAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Production of pancreatic progenitor cells from human induced pluripotent stem cells using a three-dimensional suspension bioreactor system. Mihara Y et al., 2017 Nov, J Tissue Eng Regen MedRead more