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Insulin antibody [E2E3]

Research Use Only
GTX73558
GeneTex
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Porcine
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Insulin antibody [E2E3]
  • Delivery Days Customer
    10
  • Applications
    ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    E2E3
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
  • Reactivity
    Human, Porcine
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Identification of the critical therapeutic entity in secreted Hsp90alpha that promotes wound healing in newly re-standardized healthy and diabetic pig models. OBrien K et al., 2014, PLoS One
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