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Insulin antibody [3A6]

GTX21965
GeneTex
ApplicationsELISA
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Product group Antibodies
TargetINS
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Overview

  • Supplier
    GeneTex
  • Product Name
    Insulin antibody [3A6]
  • Delivery Days Customer
    9
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    3A6
  • Conjugate
    Unconjugated
  • Gene ID3630
  • Target name
    INS
  • Target description
    insulin
  • Target synonyms
    IDDM; IDDM1; IDDM2; ILPR; insulin; IRDN; MODY10; PNDM4; preproinsulin; proinsulin
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01308
  • Protein Name
    Insulin
  • Scientific Description
    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Plasma estradiol-17beta, cortisol, and insulin concentrations and serum biochemical parameters surrounding puberty in Japanese Black beef bulls with normal and abnormal semen. Weerakoon WWPN et al., 2020 May, Theriogenology
    Read more

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