CAD antibody

GeneTex

CAD antibody

9

WB: 1-2microg/ml. ICC/IF: 10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

CAD protein; CAD trifunctional protein; CDG1Z; DEE50; EIEE50; GATD4; multifunctional protein CAD

Rabbit

IgG

CAD protein

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

-20°C or -80°C,2°C to 8°C

12352203