Caldesmon antibody [CALD1/1424R]

GeneTex

Caldesmon antibody [CALD1/1424R]

9

This antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin.

IHC-P: 1-2 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

CALD1/1424R

200 ug/ml

Unconjugated

Liquid

CALD1

caldesmon 1

caldesmon; CDM; HCAD; H-CAD; LCAD; L-CAD; NAG22; testis secretory sperm-binding protein Li 227n

Rabbit

IgG

Caldesmon

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Human, Rat

2°C to 8°C

12352203