IHC-P analysis of human endometrial carcinoma tissue section using GTX03317 Caldesmon antibody [hHCD].
IHC-P analysis of human endometrial carcinoma tissue section using GTX03317 Caldesmon antibody [hHCD].
Caldesmon antibody [hHCD]
GTX03317
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCALD1
Overview
- SupplierGeneTex
- Product NameCaldesmon antibody [hHCD]
- Delivery Days Customer9
- Antibody SpecificityThis antibody is specific to high molecular weight (120-150 kDa) h-caldesmon. The h-caldesmon variant is predominantly expressed in smooth muscle, whereas l-caldesmon (71-80 kD) is found in non-muscle tissue and cells.
- Application Supplier NoteIHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDhHCD
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID800
- Target nameCALD1
- Target descriptioncaldesmon 1
- Target synonymscaldesmon; CDM; HCAD; H-CAD; LCAD; L-CAD; NAG22; testis secretory sperm-binding protein Li 227n
- HostMouse
- IsotypeIgG1
- Protein IDQ05682
- Protein NameCaldesmon
- Scientific DescriptionThis gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203