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Immunohistochemistry analysis of human spleen tissue stained with Calnexin, pAb at 10microg/ml.
Immunohistochemistry analysis of human spleen tissue stained with Calnexin, pAb at 10microg/ml.
Immunohistochemistry analysis of human spleen tissue stained with Calnexin, pAb at 10microg/ml.

Calnexin antibody

GTX13504
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
TargetCANX
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Overview

  • Supplier
    GeneTex
  • Product Name
    Calnexin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: Use at a dilution of 1/100. ICC: Use at a dilution of 1/200. IP: Use at a dilution of 1/100. WB: Use at a dilution of 1/2000 (this dilution was sufficient for detection of Calnexin in 20microg of HeLa heat shocked cell lysate). Detects a band of approximately 90 kDa. (predicted molecular weight: 71 kDa). Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID821
  • Target name
    CANX
  • Target description
    calnexin
  • Target synonyms
    calnexin; CNX; epididymis secretory sperm binding protein; IP90; major histocompatibility complex class I antigen-binding protein p88; P90
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP27824
  • Protein Name
    Calnexin
  • Scientific Description
    This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing. Amabile A et al., 2016 Sep 22, Cell
    Read more
  • Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein. Clayton P et al., 2010 Jul-Aug, Nucleus
    Read more

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