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CARD10 antibody [N2C1], Internal

GTX111222
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCARD10
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Overview

  • Supplier
    GeneTex
  • Product Name
    CARD10 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.25 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID29775
  • Target name
    CARD10
  • Target description
    caspase recruitment domain family member 10
  • Target synonyms
    BIMP1, CARMA3, IMD89, caspase recruitment domain-containing protein 10, Bcl10 binding protein and activator of NFKB, CARD-containing MAGUK 3 protein, CARD-containing MAGUK protein 3, carma 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9BWT7
  • Protein Name
    Caspase recruitment domain-containing protein 10
  • Scientific Description
    The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • MALT1 is a critical mediator of PAR1-driven NF-kappaB activation and metastasis in multiple tumor types. McAuley JR et al., 2019 Dec, Oncogene
    Read more
  • Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. Kahle JJ et al., 2011 Feb 1, Hum Mol Genet
    Read more