CARD10 antibody [N2C1], Internal
![Research Use Only](static/images/certificates/ruo.jpg)
GTX111222
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCARD10
Overview
- SupplierGeneTex
- Product NameCARD10 antibody [N2C1], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.25 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID29775
- Target nameCARD10
- Target descriptioncaspase recruitment domain family member 10
- Target synonymsBcl10 binding protein and activator of NFKB; BIMP1; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; carma 3; CARMA3; caspase recruitment domain-containing protein 10
- HostRabbit
- IsotypeIgG
- Protein IDQ9BWT7
- Protein NameCaspase recruitment domain-containing protein 10
- Scientific DescriptionThe caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- MALT1 is a critical mediator of PAR1-driven NF-kappaB activation and metastasis in multiple tumor types. McAuley JR et al., 2019 Dec, OncogeneRead more
- Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. Kahle JJ et al., 2011 Feb 1, Hum Mol GenetRead more