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ProductsBack/Cardiac Troponin I antibody [10F4 (110)]

Cardiac Troponin I antibody [10F4 (110)]

GTX74745
GeneTex
ApplicationsWestern Blot, ELISA
Product group Antibodies
TargetTNNI3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cardiac Troponin I antibody [10F4 (110)]
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    10F4 (110)
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7137
  • Target name
    TNNI3
  • Target description
    troponin I3, cardiac type
  • Target synonyms
    CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI, troponin I, cardiac muscle, cardiomyopathy, dilated 2A (autosomal recessive), troponin I type 3 (cardiac)
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP19429
  • Protein Name
    Troponin I, cardiac muscle
  • Scientific Description
    Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ménendez S, Goh AM, Camus S, et al. MDM4 downregulates p53 transcriptional activity and response to stress during differentiation. Cell Cycle. 2011,10(7):1100-8.
    Read this paper

Datasheet

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