IHC-P analysis of normal human colon tissue using GTX01969 Caveolin 1 antibody [4D6]. Note cytoplasmic staining of smooth muscle and endothelium.
IHC-P analysis of normal human colon tissue using GTX01969 Caveolin 1 antibody [4D6]. Note cytoplasmic staining of smooth muscle and endothelium.
Caveolin 1 antibody [4D6]
GTX01969
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCAV1
Overview
- SupplierGeneTex
- Product NameCaveolin 1 antibody [4D6]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:4000. IHC-P: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4D6
- ConjugateUnconjugated
- Gene ID857
- Target nameCAV1
- Target descriptioncaveolin 1
- Target synonymsBSCL3; caveolin 1, caveolae protein, 22kDa; caveolin-1; cell growth-inhibiting protein 32; CGL3; LCCNS; MSTP085; PPH3; VIP21
- HostMouse
- IsotypeIgG2a
- Protein IDQ03135
- Protein NameCaveolin-1
- Scientific DescriptionThe scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203