CBR1 Polyclonal Antibody

Reddot Biotech

CBR1 Polyclonal Antibody

5

0.3 mg/ml

CBR1

carbonyl reductase 1

15-hydroxyprostaglandin dehydrogenase; 20-beta-hydroxysteroid dehydrogenase; carbonyl reductase (NADPH) 1; carbonyl reductase [NADPH] 1; CBR; epididymis secretory sperm binding protein; hCBR1; NADPH-dependent carbonyl reductase 1; PG-9-KR; prostaglandin 9-ketoreductase; prostaglandin-E(2) 9-reductase; SDR21C1; short chain dehydrogenase/reductase family 21C member 1

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.

-20°C

12352203