Bio-Connect

CBS antibody [GT519]

GTX628777
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetCBS
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Overview

  • Supplier
    GeneTex
  • Product Name
    CBS antibody [GT519]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT519
  • Concentration
    0.97 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID875
  • Target name
    CBS
  • Target description
    cystathionine beta-synthase
  • Target synonyms
    beta-thionase; CBSL; cystathionine beta-synthase; Cystathionine beta-synthase-like protein; HIP4; methylcysteine synthase; serine sulfhydrase
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP0DN79
  • Protein Name
    Cystathionine beta-synthase-like protein
  • Scientific Description
    The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines. Zheng J et al., 2021 Jul 13, Cell Death Dis
    Read more
  • Effect of endotoxemia in mice genetically deficient in cystathionine-gamma-lyase, cystathionine-beta-synthase or 3-mercaptopyruvate sulfurtransferase. Ahmad A et al., 2016 Dec, Int J Mol Med
    Read more
  • Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells. Pincini A et al., 2013 Aug 1, Cell Cycle
    Read more