Immunofluorescence analysis of C6 cells using CBS Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
CBS Polyclonal Antibody
E-AB-60308
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCBS Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.
- UNSPSC12352203