Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CCDC88A Polyclonal Antibody at dilution 1:50
CCDC88A Polyclonal Antibody
E-AB-13059
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCCDC88A Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration1mg/ml
- Scientific DescriptionThis gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UNSPSC12352203