Girdin (phospho Ser1417) antibody

GeneTex

Girdin (phospho Ser1417) antibody

9

IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CCDC88A

coiled-coil and HOOK domain protein 88A

APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212, PEHO, PEHOL, girdin, AKT-phosphorylation enhancer, Hook-related protein 1, coiled-coil domain containing 88A, g alpha-interacting vesicle-associated protein, girders of actin filaments

Rabbit

IgG

Girdin

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

-20°C or -80°C,2°C to 8°C

12352203