IHC-P analysis of human breast carcinoma tissue using GTX55363 Girdin (phospho Ser1417) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
IHC-P analysis of human breast carcinoma tissue using GTX55363 Girdin (phospho Ser1417) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
Girdin (phospho Ser1417) antibody
GTX55363
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCCDC88A
Overview
- SupplierGeneTex
- Product NameGirdin (phospho Ser1417) antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID55704
- Target nameCCDC88A
- Target descriptioncoiled-coil domain containing 88A
- Target synonymsAKT-phosphorylation enhancer; APE; g alpha-interacting vesicle-associated protein; girders of actin filaments; girdin; GIV; GRDN; HkRP1; Hook-related protein 1; KIAA1212; PEHO; PEHOL
- HostRabbit
- IsotypeIgG
- Protein IDQ3V6T2
- Protein NameGirdin
- Scientific DescriptionThis gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203