CCT244747 [1404095-34-6]
SYN-1216
CAS Number1404095-34-6
Product group Chemicals
Estimated Purity>95%
Molecular Weight408.5
Overview
- SupplierSYNkinase
- Product NameCCT244747 [1404095-34-6]
- Delivery Days Customer10
- CAS Number1404095-34-6
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationWarning
- Molecular FormulaC20H24N8O2
- Molecular Weight408.5
- Scientific DescriptionCCT244747 is a novel, potent, highly selective, orally active, ATP competitive CHK1 inhibitor. CCT244747 can inhibit cellular CHK1 activity with an IC50 of 29-170nM. In multiple tumour cell models, this has the effect of significantly enhancing the cytotoxicity of several anticancer drugs (such as gemcitabine and irinotecan) and abrogating drug-induced S and G2 arrest. - Chemical. CAS: 1404095-34-6. Formula: C20H24N8O2. MW: 408.5. CCT244747 is a novel, potent, highly selective, orally active, ATP competitive CHK1 inhibitor. CCT244747 can inhibit cellular CHK1 activity with an IC50 of 29-170nM. In multiple tumour cell models, this has the effect of significantly enhancing the cytotoxicity of several anticancer drugs (such as gemcitabine and irinotecan) and abrogating drug-induced S and G2 arrest.
- Storage Instruction2°C to 8°C
- UNSPSC51202000