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Western blot analysis of extracts of various cell lines using CD10/MME Polyclonal Antibody at 1:500 dilution.
Western blot analysis of extracts of various cell lines using CD10/MME Polyclonal Antibody at 1:500 dilution.
Western blot analysis of extracts of various cell lines using CD10/MME Polyclonal Antibody at 1:500 dilution.

CD10 Polyclonal Antibody

E-AB-61049
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    CD10 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5 untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.
  • UNSPSC
    12352203