CD105 antibody [MJ7/18]

GeneTex

CD105 antibody [MJ7/18]

9

FCM: 1-4 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

MJ7/18

1 mg/ml

Unconjugated

Eng

endoglin

CD105, Endo, S-endoglin, endoglin, cell surface MJ7/18 antigen, transmembrane glycoprotein

Rat

IgG2a

Endoglin

Enables protein homodimerization activity and transforming growth factor beta binding activity. Involved in several processes, including circulatory system development; positive regulation of cell differentiation; and regulation of gene expression. Acts upstream of or within angiogenesis; cell migration involved in endocardial cushion formation; and positive regulation of angiogenesis. Located in endothelial microparticle. Is expressed in several structures, including aorta-gonad-mesonephros; brain; cardiovascular system; extraembryonic component; and liver. Used to study arteriovenous malformations of the brain and hereditary hemorrhagic telangiectasia. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; hemangioma (multiple); and hereditary hemorrhagic telangiectasia. Orthologous to human ENG (endoglin). [provided by Alliance of Genome Resources, Jul 2025]

Human, Mouse, Rat

2°C to 8°C

41116161