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CD11a antibody [38] (Azide free)

Name: CD11a antibody [38] (Azide free)
SKU: GTX75442_G10
Availability: BackOrder

GTX75442

ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking

Product group Antibodies

ReactivityHuman, Mouse

TargetITGAL

Overview

Supplier
GeneTex
Product Name
CD11a antibody [38] (Azide free)
Delivery Days Customer
9
Application Supplier Note
FACS: 1/50-1/100. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
38
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID3683
Target name
ITGAL
Target description
integrin subunit alpha L
Target synonyms
CD11A, LFA-1, LFA1A, integrin alpha-L, CD11 antigen-like family member A, LFA-1 alpha, LFA-1A, antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide, integrin gene promoter, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, lymphocyte function-associated antigen 1, alpha polypeptide
Host
Mouse
Isotype
IgG2a
Protein IDP20701
Protein Name
Integrin alpha-L
Scientific Description
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Li L, Chen Y, Fu Q, et al. Decellularized extracellular matrix loaded with IPFP-SC for repairing rabbit osteochondral defects. Am J Transl Res. 2021,13(10):11026-11047.
Read this paper
Lehtonen J, Potrzebowska K, Samuelsson M, et al. Integrin Dependent RhoB Activation Assay Using Leukocytes. Bio Protoc. 2018,8(23):e3105. doi: 10.21769/BioProtoc.3105
Read this paper
Monel B, McKeon A, Lamothe-Molina P, et al. HIV Controllers Exhibit Effective CD8(+) T Cell Recognition of HIV-1-Infected Non-activated CD4(+) T Cells. Cell Rep. 2019,27(1):142-153.e4. doi: 10.1016/j.celrep.2019.03.016
Read this paper
Pathak SK, Sköld AE, Mohanram V, et al. Activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN), and β2 integrins. J Biol Chem. 2012,287(17):13731-42. doi: 10.1074/jbc.M111.336545
Read this paper
Tran DQ, Glass DD, Uzel G, et al. Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function. J Immunol. 2009,182(5):2929-38. doi: 10.4049/jimmunol.0803827
Read this paper
Hou Y, Rabquer BJ, Gerber ML, et al. Junctional adhesion molecule-A is abnormally expressed in diffuse cutaneous systemic sclerosis skin and mediates myeloid cell adhesion. Ann Rheum Dis. 2010,69(1):249-54. doi: 10.1136/ard.2008.102624
Read this paper

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CD11a antibody [38] (Azide free)

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