ProductsBack/CD11c antibody [N418] (FITC)

FACS analysis of C57Bl/6 splenocytes stained APC anti-mouse MHC Class II antibody, followed by staining with GTX74938 CD11c antibody [N418] (FITC). Right panel : Co-stained with APC anti-mouse MHC Class II antibody and GTX74938 Left panel : Co-stained with APC anti-mouse MHC Class II antibody and FITC Armenian hamster IgG isotype control Antibody amount : 0.25 μg

CD11c antibody [N418] (FITC)

GTX74938

ApplicationsFlow Cytometry

Product group Antibodies

ReactivityMouse

TargetItgax

Overview

Supplier
GeneTex
Product Name
CD11c antibody [N418] (FITC)
Delivery Days Customer
9
Applications
Flow Cytometry
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
N418
Concentration
0.5 mg/ml
Conjugate
FITC
Gene ID16411
Target name
Itgax
Target description
integrin alpha X
Target synonyms
Cd11c, Cr4, N418, integrin alpha-X, CD11 antigen-like family member C, CD11C (p150) alpha polypeptide, complement receptor 4, integrin aX, leukocyte adhesion glycoprotein p150,95 alpha chain, leukocyte adhesion receptor p150,95
Host
Hamster
Isotype
IgG2
Protein IDQ9QXH4
Protein Name
Integrin alpha-X
Reactivity
Mouse
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Matson KJE, Russ DE, Kathe C, et al. Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons. Nat Commun. 2022,13(1):5628. doi: 10.1038/s41467-022-33184-1
Read this paper
Ohno Y, Toyoshima Y, Yurino H, et al. Lack of interleukin-6 in the tumor microenvironment augments type-1 immunity and increases the efficacy of cancer immunotherapy. Cancer Sci. 2017,108(10):1959-1966. doi: 10.1111/cas.13330
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Lin YL, Tsai NM, Hsieh CH, et al. In vivo amelioration of endogenous antitumor autoantibodies via low-dose P4N through the LTA4H/activin A/BAFF pathway. Proc Natl Acad Sci U S A. 2016,113(48):E7798-E7807.
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Ortiz ML, Kumar V, Martner A, et al. Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells. J Exp Med. 2015,212(3):351-67. doi: 10.1084/jem.20140835
Read this paper
Ibrahim MK, Barnes JL, Osorio EY, et al. Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection. Infect Immun. 2014,82(8):3098-112. doi: 10.1128/IAI.01778-14
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Jackson NP, Kang YH, Lapaque N, et al. Salmonella polarises peptide-MHC-II presentation towards an unconventional Type B CD4+ T-cell response. Eur J Immunol. 2013,43(4):897-906. doi: 10.1002/eji.201242983
Read this paper
Guerriero JL, Ditsworth D, Catanzaro JM, et al. DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. J Immunol. 2011,186(6):3517-26. doi: 10.4049/jimmunol.1003267
Read this paper
Elftman MD, Norbury CC, Bonneau RH, et al. Corticosterone impairs dendritic cell maturation and function. Immunology. 2007,122(2):279-90.
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Sadhu C, Ting HJ, Lipsky B, et al. CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. J Leukoc Biol. 2007,81(6):1395-403.
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Hagnerud S, Manna PP, Cella M, et al. Deficit of CD47 results in a defect of marginal zone dendritic cells, blunted immune response to particulate antigen and impairment of skin dendritic cell migration. J Immunol. 2006,176(10):5772-8.
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CD11c antibody [N418] (FITC)

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