CD11c antibody [N418]
GTX74940
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
TargetItgax
Overview
- SupplierGeneTex
- Product NameCD11c antibody [N418]
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDN418
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID16411
- Target nameItgax
- Target descriptionintegrin alpha X
- Target synonymsCd11c, Cr4, N418, integrin alpha-X, CD11 antigen-like family member C, CD11C (p150) alpha polypeptide, complement receptor 4, integrin aX, leukocyte adhesion glycoprotein p150,95 alpha chain, leukocyte adhesion receptor p150,95
- HostHamster
- IsotypeIgG2
- Protein IDQ9QXH4
- Protein NameIntegrin alpha-X
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
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- Matson KJE, Russ DE, Kathe C, et al. Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons. Nat Commun. 2022,13(1):5628. doi: 10.1038/s41467-022-33184-1Read this paper
- Ohno Y, Toyoshima Y, Yurino H, et al. Lack of interleukin-6 in the tumor microenvironment augments type-1 immunity and increases the efficacy of cancer immunotherapy. Cancer Sci. 2017,108(10):1959-1966. doi: 10.1111/cas.13330Read this paper
- Lin YL, Tsai NM, Hsieh CH, et al. In vivo amelioration of endogenous antitumor autoantibodies via low-dose P4N through the LTA4H/activin A/BAFF pathway. Proc Natl Acad Sci U S A. 2016,113(48):E7798-E7807.Read this paper
- Ortiz ML, Kumar V, Martner A, et al. Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells. J Exp Med. 2015,212(3):351-67. doi: 10.1084/jem.20140835Read this paper
- Ibrahim MK, Barnes JL, Osorio EY, et al. Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection. Infect Immun. 2014,82(8):3098-112. doi: 10.1128/IAI.01778-14Read this paper
- Jackson NP, Kang YH, Lapaque N, et al. Salmonella polarises peptide-MHC-II presentation towards an unconventional Type B CD4+ T-cell response. Eur J Immunol. 2013,43(4):897-906. doi: 10.1002/eji.201242983Read this paper
- Guerriero JL, Ditsworth D, Catanzaro JM, et al. DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. J Immunol. 2011,186(6):3517-26. doi: 10.4049/jimmunol.1003267Read this paper
- Elftman MD, Norbury CC, Bonneau RH, et al. Corticosterone impairs dendritic cell maturation and function. Immunology. 2007,122(2):279-90.Read this paper

![FACS analysis of C57Bl/6 splenocytes stained APC MHC Class II antibody, followed by staining with GTX74936 CD11c antibody [N418] (Biotin). Right panel : Co-stained with APC MHC Class II antibody and GTX74936 Left panel : Co-stained with APC MHC Class II antibody and Biotin Armenian hamster IgG isotype control Antibody amount : 0.03 μg](https://www.genetex.com/upload/website/prouct_img/normal/GTX74936/GTX74936_20201020_FACS_17_w_23061322_912.webp)
![FACS analysis of C57Bl/6 splenocytes stained APC anti-mouse MHC Class II antibody, followed by staining with GTX74938 CD11c antibody [N418] (FITC). Right panel : Co-stained with APC anti-mouse MHC Class II antibody and GTX74938 Left panel : Co-stained with APC anti-mouse MHC Class II antibody and FITC Armenian hamster IgG isotype control Antibody amount : 0.25 μg](https://www.genetex.com/upload/website/prouct_img/normal/GTX74938/GTX74938_20201020_FACS_28_w_23061322_813.webp)
![FACS analysis of C57Bl/6 splenocytes stained APC anti-mouse MHC Class II antibody, followed by staining with GTX74941 CD11c antibody [N418] (PE). Right panel : Co-stained with APC anti-mouse MHC Class II antibody and GTX74941 Left panel : Co-stained with APC anti-mouse MHC Class II antibody and PE Armenian hamster IgG isotype control Antibody amount : 0.25 μg](https://www.genetex.com/upload/website/prouct_img/normal/GTX74941/GTX74941_20201020_FACS_52_w_23061322_711.webp)