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ProductsBack/CD11c antibody [N418]

CD11c antibody [N418]

GTX74940
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
DownloadDatasheet
Product group Antibodies
ReactivityMouse
TargetItgax
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD11c antibody [N418]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    N418
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID16411
  • Target name
    Itgax
  • Target description
    integrin alpha X
  • Target synonyms
    AI449405; CD11 antigen-like family member C; Cd11c; CD11C (p150) alpha polypeptide; complement receptor 4; Cr4; integrin alpha-X; integrin aX; leukocyte adhesion glycoprotein p150,95 alpha chain; leukocyte adhesion receptor p150,95; N418
  • Host
    Hamster
  • Isotype
    IgG2
  • Protein IDQ9QXH4
  • Protein Name
    Integrin alpha-X
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • CDC7 inhibition induces replication stress-mediated aneuploid cells with an inflammatory phenotype sensitizing tumors to immune checkpoint blockade.
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  • Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis.
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  • Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons.
    Read more
  • Lack of interleukin-6 in the tumor microenvironment augments type-1 immunity and increases the efficacy of cancer immunotherapy. Ohno Y et al., 2017 Oct, Cancer Sci
    Read more
  • In vivo amelioration of endogenous antitumor autoantibodies via low-dose P4N through the LTA4H/activin A/BAFF pathway. Lin YL et al., 2016 Nov 29, Proc Natl Acad Sci U S A
    Read more
  • Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells. Ortiz ML et al., 2015 Mar 9, J Exp Med
    Read more
  • Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection. Ibrahim MK et al., 2014 Aug, Infect Immun
    Read more
  • Salmonella polarises peptide-MHC-II presentation towards an unconventional Type B CD4+ T-cell response. Jackson NP et al., 2013 Apr, Eur J Immunol
    Read more
  • DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. Guerriero JL et al., 2011 Mar 15, J Immunol
    Read more
  • Corticosterone impairs dendritic cell maturation and function. Elftman MD et al., 2007 Oct, Immunology
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