CD156c Polyclonal Antibody
RD77670A
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetADAM10
Overview
- SupplierReddot Biotech
- Product NameCD156c Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID102
- Target nameADAM10
- Target descriptionADAM metallopeptidase domain 10
- Target synonymsa disintegrin and metalloprotease domain 10; AD10; AD18; CD156c; CDw156; disintegrin and metalloproteinase domain-containing protein 10; HsT18717; kuz; kuzbanian protein homolog; MADM; mammalian disintegrin-metalloprotease; RAK
- HostRabbit
- IsotypeIgG
- Scientific DescriptionMembers of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at 76-Ala- - -Val-77 to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203