Anti-Hu CD18 Purified Low Endotoxin

Biorbyt

Anti-Hu CD18 Purified Low Endotoxin

16

Low Endotoxin, Azide free format. Product does not contain preservatives and is intended primarily for functional applications. Preservative containing buffers are available for IHC applications. Functional application: The antibody MEM-148 induces homotypic cell aggregation and high-affinity LFA-1 conformation in resting leukocytes. Flow cytometry: Recommended dilution: 8 μg/ml. The antibody MEM-148 is an excellent marker of activated myeloid cells. Western blotting: Non-reducing conditions. FA, FC, IP, WB

Research Use Only

Monoclonal

MEM-148

1 mg/ml

Unconjugated

ITGB2

integrin subunit beta 2

CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, integrin beta-2, cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor), complement component 3 receptor 3 and 4 subunit, complement receptor C3 beta-subunit, integrin beta chain, beta 2, integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C

IgG1

Integrin beta-2

Mouse monoclonal antibody to CD18 which belongs to the integrin beta chain family. Defects in ITGB2 are the cause of leukocyte adhesion deficiency type 1 (LAD1). CD18 is involved in cellular adhesion and the immune response. CD18 and the a subunits are expressed broadly by all leukocytes with NK and T cells showing higher density of surface expression.

Human

-20°C,2°C to 8°C

12352203