CD18 antibody [YFC118.3]
GTX76240
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
TargetITGB2
Overview
- SupplierGeneTex
- Product NameCD18 antibody [YFC118.3]
- Delivery Days Customer9
- Application Supplier NoteIHC-Fr: 1/1,000-1/5,000. FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDYFC118.3
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3689
- Target nameITGB2
- Target descriptionintegrin subunit beta 2
- Target synonymsCD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, integrin beta-2, cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor), complement component 3 receptor 3 and 4 subunit, complement receptor C3 beta-subunit, integrin beta chain, beta 2, integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
- HostRat
- IsotypeIgG2b
- Protein IDP05107
- Protein NameIntegrin beta-2
- Scientific DescriptionThis gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. Sindrilaru A et al., 2011 Mar, J Clin InvestRead this paper


![FACS analysis of Jurkat cells using GTX15770 CD18 antibody [TS1/18] compared to an isotype control (blue). Dilution : 0.5 ug/test for 60 min at room temperature Fixation : 2% paraformaldehyde](https://www.genetex.com/upload/website/prouct_img/normal/GTX15770/GTX15770_113_FACS_w_23060620_708.webp)
![FACS analysis of human peripheral blood using GTX18238 CD18 antibody [MEM-48] (FITC).](https://www.genetex.com/upload/website/prouct_img/normal/GTX18238/GTX18238_20191025_AP_006_137_w_23060620_737.webp)
![WB analysis of various samples (non-reducing) using GTX20657 CD18 antibody [MEM-48]. Lane 1 : KG-1a cell lysate Lane 2 : HPB-ALL cell lysate](https://www.genetex.com/upload/website/prouct_img/normal/GTX20657/GTX20657_20191025_AP_001_149_w_23060620_756.webp)

![ICC/IF analysis of HL60 cells using GTX83119 CD18 antibody [10E12]. Green : CD18 Blue: DRAQ5 fluorescent DNA dye](https://www.genetex.com/upload/website/prouct_img/normal/GTX83119/GTX83119_20170912_ICCIF_1_w_23061322_504.webp)