CD18(68-5A5), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040321
ApplicationsFunctional Assay, Flow Cytometry
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetITGB2
Overview
- SupplierBiotium
- Product NameCD18(68-5A5), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsFunctional Assay, Flow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID68-5A5
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID3689
- Target nameITGB2
- Target descriptionintegrin subunit beta 2
- Target synonymsCD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; integrin beta chain, beta 2; integrin beta-2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; LCAMB; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; MAC-1; MF17; MFI7; truncated integrin beta-2
- HostMouse
- IsotypeIgG2a
- Protein IDP05107
- Protein NameIntegrin beta-2
- Scientific DescriptionThis antibody recognizes a transmembrane glycoprotein of 95 kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203