CD28(C28/76), Biotin conjugate, 0.1mg/mL [26628-22-8]

Biotium

CD28(C28/76), Biotin conjugate, 0.1mg/mL

9

Flow Cytometry

Research Use Only

Monoclonal

C28/76

0.1 mg/ml

Biotin

CD28

CD28 molecule

T-cell-specific surface glycoprotein CD28; Tp44

Mouse

IgG1

T-cell-specific surface glycoprotein CD28

Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C

12352203