Bio-Connect

CD2AP Antibody

OAAN02433
Aviva Systems Biology
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCD2AP
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Overview

  • Supplier
    Aviva Systems Biology
  • Product Name
    CD2AP Antibody
  • Delivery Days Customer
    23
  • Application Supplier Note
    WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Format
    Liquid
  • Gene ID23607
  • Target name
    CD2AP
  • Target description
    CD2 associated protein
  • Target synonyms
    CMS, CD2-associated protein, Cas ligand with multiple Src homology (SH) 3 domains, Cas ligand with multiple Src homology 3 (SH3) domains, adapter protein CMS, cas ligand with multiple SH3 domains
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y5K6
  • Protein Name
    CD2-associated protein
  • Scientific Description
    This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    41116161