The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA243594(CD33 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
CD33 Antibody
CSB-PA243594
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCD33
Overview
- SupplierCusabio
- Product NameCD33 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID945
- Target nameCD33
- Target descriptionCD33 molecule
- Target synonymsCD33 antigen (gp67); CD33 molecule transcript; gp67; myeloid cell surface antigen CD33; p67; sialic acid-binding Ig-like lectin 3; SIGLEC3; SIGLEC-3
- HostRabbit
- IsotypeIgG
- Protein IDP20138
- Protein NameMyeloid cell surface antigen CD33
- Scientific DescriptionCD33 or Siglec-3 is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203