CD4, Mouse (T-Cell Marker)(GK1.5), CF700 conjugate, 0.1mg/mL [26628-22-8]

Biotium

CD4, Mouse (T-Cell Marker)(GK1.5), CF700 conjugate, 0.1mg/mL

9

Functional Assay, Flow Cytometry

Research Use Only

Monoclonal

GK1.5

0.1 mg/ml

Other Conjugate

FCGR1A

Fc fragment of IgG receptor Ia

CD64; CD64A; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc gamma receptor Ia; Fc-gamma receptor I A1; Fc-gamma RI; fc-gamma RIA; FcgammaRI; fcgammaRIa; FCRI; high affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I

Rat

IgG2b

T-cell surface glycoprotein CD4

CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C

12352203