CD44 antibody
GTX102111
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Rabbit, Rat
TargetCD44
Overview
- SupplierGeneTex
- Product NameCD44 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID960
- Target nameCD44
- Target descriptionCD44 molecule (IN blood group)
- Target synonymsCDW44, CSPG8, ECM-III, ECMR-III, H-CAM, HCELL, HUTCH-1, HUTCH-I, Hermes-1, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CD44 antigen, CD44 molecule (Indian blood group), GP90 lymphocyte homing/adhesion receptor, Hermes antigen, In(Lu) related-p80, Indian blood group antigen, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, epican, extracellular matrix receptor III, hematopoietic cell E- and L-selectin ligand, heparan sulfate proteoglycan, homing cell adhesion molecule, homing function and Indian blood group system, hyaluronate receptor, phagocyte glycoprotein 1, phagocytic glycoprotein 1, soluble CD44
- HostRabbit
- IsotypeIgG
- Protein IDP16070
- Protein NameCD44 antigen
- Scientific DescriptionThe protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq]
- ReactivityHuman, Rabbit, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Şen Ö, Emanet M, Mazzuferi M, et al. Microglia Polarization and Antiglioma Effects Fostered by Dual Cell Membrane-Coated Doxorubicin-Loaded Hexagonal Boron Nitride Nanoflakes. ACS Appl Mater Interfaces. 2023,15(50):58260-58273. doi: 10.1021/acsami.3c17097Read this paper
- Vadhan A, Hou MF, Vijayaraghavan P, et al. CD44 Promotes Breast Cancer Metastasis through AKT-Mediated Downregulation of Nuclear FOXA2. Biomedicines. 2022,10(10). doi: 10.3390/biomedicines10102488Read this paper
- Chu PY, Huang WC, Tung SL, et al. IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis. Cell Biosci. 2022,12(1):124. doi: 10.1186/s13578-022-00858-8Read this paper
- Wuputra K, Hsiao PJ, Chang WT, et al. FOXM1-CD44 Signaling Is Critical for the Acquisition of Regorafenib Resistance in Human Liver Cancer Cells. Int J Mol Sci. 2022,23(14). doi: 10.3390/ijms23147782Read this paper
- Howley BV, Mohanty B, Dalton A, et al. The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression. Oncogene. 2022,41(12):1679-1690. doi: 10.1038/s41388-022-02199-9Read this paper
- Young MJ, Chen YC, Wang SA, et al. Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression. J Biomed Sci. 2022,29(1):3. doi: 10.1186/s12929-022-00787-1Read this paper
- Chen YA, Ho CL, Ku MT, et al. Detection of cancer stem cells by EMT-specific biomarker-based peptide ligands. Sci Rep. 2021,11(1):22430. doi: 10.1038/s41598-021-01138-0Read this paper
- Mir C, Garcia-Mayea Y, Garcia L, et al. SDCBP Modulates Stemness and Chemoresistance in Head and Neck Squamous Cell Carcinoma through Src Activation. Cancers (Basel). 2021,13(19). doi: 10.3390/cancers13194952Read this paper
- Offeddu GS, Hajal C, Foley CR, et al. The cancer glycocalyx mediates intravascular adhesion and extravasation during metastatic dissemination. Commun Biol. 2021,4(1):255. doi: 10.1038/s42003-021-01774-2Read this paper
- Yeh BW, Yu LE, Li CC, et al. The protoapigenone analog WYC0209 targets CD133+ cells: A potential adjuvant agent against cancer stem cells in urothelial cancer therapy. Toxicol Appl Pharmacol. 2020,402:115129. doi: 10.1016/j.taap.2020.115129Read this paper
Datasheet
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