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WB analysis of various sample lysates using GTX53912 CD47 antibody. Dilution : 1:500 Loading : 25microg per lane
WB analysis of various sample lysates using GTX53912 CD47 antibody. Dilution : 1:500 Loading : 25microg per lane
WB analysis of various sample lysates using GTX53912 CD47 antibody. Dilution : 1:500 Loading : 25microg per lane

CD47 antibody

GTX53912
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCD47
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD47 antibody
  • Delivery Days Customer
    7
  • Application Supplier Note
    WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID961
  • Target name
    CD47
  • Target description
    CD47 molecule
  • Target synonyms
    antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 glycoprotein; IAP; integrin associated protein; integrin-associated signal transducer; leukocyte surface antigen CD47; MER6; OA3; Rh-related antigen
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ08722
  • Protein Name
    Leukocyte surface antigen CD47
  • Scientific Description
    This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Rapamycin and hydroxychloroquine combination alters macrophage polarization and sensitizes glioblastoma to immune checkpoint inhibitors. Hsu SPC et al., 2020 Feb, J Neurooncol
    Read more
  • RRx-001 Acts as a Dual Small Molecule Checkpoint Inhibitor by Downregulating CD47 on Cancer Cells and SIRP-alpha on Monocytes/Macrophages. Cabrales P, 2019 Apr, Transl Oncol
    Read more
  • Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type IIb and tuberous sclerosis complex. Sun FJ et al., 2016 Apr 19, J Neuroinflammation
    Read more