CD6 (Negative Marker of T-regulatory Cells)(SPV-L14), 1mg/mL [26628-22-8]

Biotium

CD6 (Negative Marker of T-regulatory Cells)(SPV-L14), 1mg/mL [26628-22-8]

9

Functional Assay, Flow Cytometry, ImmunoFluorescence

26628-22-8

Research Use Only

Monoclonal

SPV-L14

1 mg/ml

CD6

CD6 molecule

TP120, T-cell differentiation antigen CD6, CD6 antigen, T12

Mouse

IgG1

T-cell differentiation antigen CD6

CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Animal

Human, Mouse

-20°C

41116161