
Western blot analysis of extracts from HuvEc cells, using CD79A antibody.
CD79A Antibody
CSB-PA165334
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetCD79A
Overview
- SupplierCusabio
- Product NameCD79A Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID973
- Target nameCD79A
- Target descriptionCD79a molecule
- Target synonymsB-cell antigen receptor complex-associated protein alpha chain; CD79a antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha; IGA; ig-alpha; MB-1; MB-1 membrane glycoprotein; membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
- HostRabbit
- IsotypeIgG
- Protein IDP11912
- Protein NameB-cell antigen receptor complex-associated protein alpha chain
- Scientific DescriptionRequired in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells. Leduc I., Clin. Exp. Immunol. 90:141-146(1992). Mueller B.S., Eur. J. Immunol. 22:1621-1625(1992). Flaswinkel H., Immunogenetics 36:266-269(1992).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203