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CD8 alpha antibody [53-6.7]

GTX00604
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
TargetCd8a
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD8 alpha antibody [53-6.7]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    53-6.7
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID12525
  • Target name
    Cd8a
  • Target description
    CD8 subunit alpha
  • Target synonyms
    Ly-2, Ly-35, Ly-B, Lyt-2, T-cell surface glycoprotein CD8 alpha chain, CD8 antigen, alpha chain, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), T-cell surface glycoprotein Lyt-2
  • Host
    Rat
  • Isotype
    IgG2a
  • Protein IDP01731
  • Protein Name
    T-cell surface glycoprotein CD8 alpha chain
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Shevtsov M, Pitkin E, Ischenko A, et al. Ex vivo Hsp70-Activated NK Cells in Combination With PD-1 Inhibition Significantly Increase Overall Survival in Preclinical Models of Glioblastoma and Lung Cancer. Front Immunol. 2019,10:454. doi: 10.3389/fimmu.2019.00454
    Read this paper
  • Hsieh JL, Shiau AL, Lee CH, et al. CD8+ T cell-induced expression of tissue inhibitor of metalloproteinses-1 exacerbated osteoarthritis. Int J Mol Sci. 2013,14(10):19951-70. doi: 10.3390/ijms141019951
    Read this paper
  • Thaventhiran JE, Hoffmann A, Magiera L, et al. Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell. Proc Natl Acad Sci U S A. 2012,109(33):E2223-9. doi: 10.1073/pnas.1209115109
    Read this paper
  • Willinger T, Flavell RA. Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis. Proc Natl Acad Sci U S A. 2012,109(22):8670-5. doi: 10.1073/pnas.1205305109
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  • Nagashima T, Ichimiya S, Kikuchi T, et al. Arachidonate 5-lipoxygenase establishes adaptive humoral immunity by controlling primary B cells and their cognate T-cell help. Am J Pathol. 2011,178(1):222-32. doi: 10.1016/j.ajpath.2010.11.033
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  • Mochimaru H, Usui T, Yaguchi T, et al. Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2. Invest Ophthalmol Vis Sci. 2008,49(5):2172-7. doi: 10.1167/iovs.07-1396
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  • Minamimura K, Gao W, Maki T. CD4+ regulatory T cells are spared from deletion by antilymphocyte serum, a polyclonal anti-T cell antibody. J Immunol. 2006,176(7):4125-32.
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  • Fan K, Zhou M, Pathak MK, et al. Sodium stibogluconate interacts with IL-2 in anti-Renca tumor action via a T cell-dependent mechanism in connection with induction of tumor-infiltrating macrophages. J Immunol. 2005,175(10):7003-8.
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  • Nutt SL, Metcalf D, D'Amico A, et al. Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J Exp Med. 2005,201(2):221-31.
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  • Fan GC, Singh RR. Vaccination with minigenes encoding V(H)-derived major histocompatibility complex class I-binding epitopes activates cytotoxic T cells that ablate autoantibody-producing B cells and inhibit lupus. J Exp Med. 2002,196(6):731-41.
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