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ProductsBack/CDC25B antibody [EPR3459(2)]
GTX63329 WB Image
GTX63329 WB Image
GTX63329 WB Image

CDC25B antibody [EPR3459(2)]

Research Use Only
GTX63329
GeneTex
ApplicationsImmunoPrecipitation, Western Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman
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Overview

  • Supplier
    GeneTex
  • Product Name
    CDC25B antibody [EPR3459(2)]
  • Delivery Days Customer
    10
  • Applications
    ImmunoPrecipitation, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    EPR3459(2)
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process. Rodriguez A et al., 2015 Sep 18, Theor Biol Med Model
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