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Western blot analysis of extracts of various cell lines using cdc45 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using cdc45 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using cdc45 Polyclonal Antibody at 1:1000 dilution.

CDC45 Polyclonal Antibody

Research Use Only
E-AB-60574
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    CDC45 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
  • UNSPSC
    12352203