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CDK2 antibody [N1C3]

GTX101226
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityFish, Human
TargetCDK2
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Overview

  • Supplier
    GeneTex
  • Product Name
    CDK2 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1017
  • Target name
    CDK2
  • Target description
    cyclin dependent kinase 2
  • Target synonyms
    CDKN2, p33(CDK2), cyclin-dependent kinase 2, cdc2-related protein kinase, cell division protein kinase 2, p33 protein kinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP24941
  • Protein Name
    Cyclin-dependent kinase 2
  • Scientific Description
    The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq]
  • Reactivity
    Fish, Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Liu YH, Weng YP, Lin HY, et al. Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Sci Rep. 2017,7:41437. doi: 10.1038/srep41437
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  • Kuo CY, Li X, Stark JM, et al. RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner. Cell Cycle. 2016,15(6):787-98. doi: 10.1080/15384101.2016.1138184
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  • Huang AM, Kao YT, Toh S, et al. UBE2M-mediated p27(Kip1) degradation in gemcitabine cytotoxicity. Biochem Pharmacol. 2011,82(1):35-42. doi: 10.1016/j.bcp.2011.03.026
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