Bio-Connect

CEACAM1 antibody [B464M]

GTX44154
GeneTex
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCEACAM1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CEA antibody [B464M]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Does not crossreact with human leukocytes in cytofluorometry.Staining in immunohistochemistry:Brightness 80 Cytoplasmic Staining 3+ Membrane Staining 2+ Background 2+ Staining of Mucus 2+
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    B464M
  • Concentration
    5.1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID634
  • Target name
    CEACAM1
  • Target description
    CEA cell adhesion molecule 1
  • Target synonyms
    antigen CD66; BGP; BGP1; BGPI; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); CD66a antigen
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP13688
  • Protein Name
    Carcinoembryonic antigen-related cell adhesion molecule 1
  • Scientific Description
    This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203