CEACAM1 antibody [B464M]
GTX44154
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCEACAM1
Overview
- SupplierGeneTex
- Product NameCEA antibody [B464M]
- Delivery Days Customer9
- Antibody SpecificityDoes not crossreact with human leukocytes in cytofluorometry.Staining in immunohistochemistry:Brightness 80 Cytoplasmic Staining 3+ Membrane Staining 2+ Background 2+ Staining of Mucus 2+
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDB464M
- Concentration5.1 mg/ml
- ConjugateUnconjugated
- Gene ID634
- Target nameCEACAM1
- Target descriptionCEA cell adhesion molecule 1
- Target synonymsantigen CD66; BGP; BGP1; BGPI; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); CD66a antigen
- HostMouse
- IsotypeIgG1
- Protein IDP13688
- Protein NameCarcinoembryonic antigen-related cell adhesion molecule 1
- Scientific DescriptionThis gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203