CENPF antibody

GeneTex

CENPF antibody

9

WB: 1:1500 - 1:2500. ICC/IF: 1:200 - 1:1000. FACS: 1:50 - 1:200. IP: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

2.5 mg/ml

Unconjugated

CENPF

centromere protein F

CENF, CILD31, PRO1779, STROMS, hcp-1, centromere protein F, AH antigen, CENP-F kinetochore protein, cell-cycle-dependent 350K nuclear protein, centromere protein F, 350/400kDa, kinetochore protein CENPF, mitosin

Rabbit

IgG

Centromere protein F

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203