More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/CHD4 antibody

CHD4 antibody

GTX124186
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetCHD4
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    CHD4 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1108
  • Target name
    CHD4
  • Target description
    chromodomain helicase DNA binding protein 4
  • Target synonyms
    ATP-dependent helicase CHD4; CHD-4; chromodomain-helicase-DNA-binding protein 4; Mi-2 autoantigen 218 kDa protein; Mi-2b; Mi2-BETA; SIHIWES
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ14839
  • Protein Name
    Chromodomain-helicase-DNA-binding protein 4
  • Scientific Description
    The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer. Chang CL et al., 2021, Int J Biol Sci
    Read more
  • Identification of CHD4-beta1 integrin axis as a prognostic marker in triple-negative breast cancer using next-generation sequencing and bioinformatics. Ou-Yang F et al., 2019 Dec 1, Life Sci
    Read more
  • Over-Expression of CHD4 Is an Independent Biomarker of Poor Prognosis in Patients with Rectal Cancers Receiving Concurrent Chemoradiotherapy. Wang HC et al., 2019 Aug 21, Int J Mol Sci
    Read more
  • CHD4-mediated loss of E-cadherin determines metastatic ability in triple-negative breast cancer cells. Luo CW et al., 2018 Feb 1, Exp Cell Res
    Read more
  • The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer. Hou MF et al., 2017 Oct 15, Exp Cell Res
    Read more
  • Senataxin controls meiotic silencing through ATR activation and chromatin remodeling. Yeo AJ et al., 2015, Cell Discov
    Read more