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cIAP1 antibody

Name: cIAP1 antibody
SKU: GTX110087_G10
Availability: BackOrder

GTX110087

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetBIRC2

Overview

Supplier
GeneTex
Product Name
cIAP1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.56 mg/ml
Conjugate
Unconjugated
Gene ID329
Target name
BIRC2
Target description
baculoviral IAP repeat containing 2
Target synonyms
API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1, baculoviral IAP repeat-containing protein 2, IAP homolog B, IAP-2, NFR2-TRAF signalling complex protein, RING finger protein 48, RING-type E3 ubiquitin transferase BIRC2, TNFR2-TRAF-signaling complex protein 2, apoptosis inhibitor 1, cellular inhibitor of apoptosis 1, inhibitor of apoptosis protein 2
Host
Rabbit
Isotype
IgG
Protein IDQ13490
Protein Name
Baculoviral IAP repeat-containing protein 2
Scientific Description
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Liu F, Wang X, Duan J, et al. A Temporal PROTAC Cocktail-Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells. Adv Sci (Weinh). 2022,9(22):e2104823. doi: 10.1002/advs.202104823
Read this paper
Lin CY, Wang CC, Wu RC, et al. Inhibition of BIRC2 Sensitizes α7-HPV-Related Cervical Squamous Cell Carcinoma to Chemotherapy. Int J Mol Sci. 2021,22(20). doi: 10.3390/ijms222011020
Read this paper
Wu YH, Chou TF, Young L, et al. Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Cell Death Dis. 2020,11(5):305. doi: 10.1038/s41419-020-2534-9
Read this paper
Leu JS, Chen ML, Chang SY, et al. SP110b Controls Host Immunity and Susceptibility to Tuberculosis. Am J Respir Crit Care Med. 2017,195(3):369-382. doi: 10.1164/rccm.201601-0103OC
Read this paper
Fu K, Sun X, Wier EM, et al. Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation. Elife. 2016,5:pii: e15018. doi: 10.7554/eLife.15018.
Read this paper
Xu YM, Wu DD, Zheng W, et al. Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Oncotarget. 2016,7(5):6146-58. doi: 10.18632/oncotarget.6738
Read this paper
Huang YT, Chen YY, Lai YH, et al. Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Int J Mol Med. 2016,37(1):83-91. doi: 10.3892/ijmm.2015.2404
Read this paper
Budhidarmo R, Day CL. The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation. J Biol Chem. 2014,289(37):25721-36. doi: 10.1074/jbc.M113.545475
Read this paper

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cIAP1 antibody

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