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cIAP1 antibody

Research Use Only
GTX110087
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBIRC2
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Overview

  • Supplier
    GeneTex
  • Product Name
    cIAP1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.56 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID329
  • Target name
    BIRC2
  • Target description
    baculoviral IAP repeat containing 2
  • Target synonyms
    API1; apoptosis inhibitor 1; baculoviral IAP repeat-containing protein 2; cellular inhibitor of apoptosis 1; cIAP1; c-IAP1; HIAP2; Hiap-2; IAP homolog B; IAP-2; inhibitor of apoptosis protein 2; MIHB; NFR2-TRAF signalling complex protein; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; RNF48; TNFR2-TRAF-signaling complex protein 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13490
  • Protein Name
    Baculoviral IAP repeat-containing protein 2
  • Scientific Description
    The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A Temporal PROTAC Cocktail-Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells. Liu F et al., 2022 Aug, Adv Sci (Weinh)
    Read more
  • Inhibition of BIRC2 Sensitizes alpha7-HPV-Related Cervical Squamous Cell Carcinoma to Chemotherapy. Lin CY et al., 2021 Oct 13, Int J Mol Sci
    Read more
  • Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Wu YH et al., 2020 May 4, Cell Death Dis
    Read more
  • SP110b Controls Host Immunity and Susceptibility to Tuberculosis. Leu JS et al., 2017 Feb 1, Am J Respir Crit Care Med
    Read more
  • Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-kappaB activation. Fu K et al., 2016 Jul 25, Elife
    Read more
  • Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Xu YM et al., 2016 Feb 2, Oncotarget
    Read more
  • Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Huang YT et al., 2016 Jan, Int J Mol Med
    Read more
  • The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation. Budhidarmo R et al., 2014 Sep 12, J Biol Chem
    Read more