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cIAP1 antibody

Name: cIAP1 antibody
SKU: GTX110087_G10
Availability: BackOrder

GTX110087

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetBIRC2

Overview

Supplier
GeneTex
Product Name
cIAP1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.56 mg/ml
Conjugate
Unconjugated
Gene ID329
Target name
BIRC2
Target description
baculoviral IAP repeat containing 2
Target synonyms
API1; apoptosis inhibitor 1; baculoviral IAP repeat-containing protein 2; cellular inhibitor of apoptosis 1; cIAP1; c-IAP1; HIAP2; Hiap-2; IAP homolog B; IAP-2; inhibitor of apoptosis protein 2; MIHB; NFR2-TRAF signalling complex protein; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; RNF48; TNFR2-TRAF-signaling complex protein 2
Host
Rabbit
Isotype
IgG
Protein IDQ13490
Protein Name
Baculoviral IAP repeat-containing protein 2
Scientific Description
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

A Temporal PROTAC Cocktail-Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells. Liu F et al., 2022 Aug, Adv Sci (Weinh)
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Inhibition of BIRC2 Sensitizes alpha7-HPV-Related Cervical Squamous Cell Carcinoma to Chemotherapy. Lin CY et al., 2021 Oct 13, Int J Mol Sci
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Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Wu YH et al., 2020 May 4, Cell Death Dis
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SP110b Controls Host Immunity and Susceptibility to Tuberculosis. Leu JS et al., 2017 Feb 1, Am J Respir Crit Care Med
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Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-kappaB activation. Fu K et al., 2016 Jul 25, Elife
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Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Xu YM et al., 2016 Feb 2, Oncotarget
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Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Huang YT et al., 2016 Jan, Int J Mol Med
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The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation. Budhidarmo R et al., 2014 Sep 12, J Biol Chem
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