Western Blot Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, Rat brain tissue All lanes: CKAP5 antibody at 6microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 226, 219, 227 kDa Observed band size: 226 kDa
CKAP5 Antibody
CSB-PA617899LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCKAP5
Overview
- SupplierCusabio
- Product NameCKAP5 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9793
- Target nameCKAP5
- Target descriptioncytoskeleton associated protein 5
- Target synonymsCHTOG; ch-TOG; colonic and hepatic tumor overexpressed gene protein; colonic and hepatic tumor over-expressed gene protein; cytoskeleton-associated protein 5; MSPS; TOG; TOGp
- HostRabbit
- IsotypeIgG
- Protein IDQ14008
- Protein NameCytoskeleton-associated protein 5
- Scientific DescriptionBinds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed:27156448).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203