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Coagulation Factor II antibody [10B23]

GTX52644
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
TargetF2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Coagulation Factor II antibody [10B23]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    10B23
  • Concentration
    500 ug/ml
  • Conjugate
    Unconjugated
  • Gene ID2147
  • Target name
    F2
  • Target description
    coagulation factor II, thrombin
  • Target synonyms
    prepro-coagulation factor II; prothrombin; prothrombin B-chain; PT; RPRGL2; THPH1; thrombin factor II
  • Host
    Mouse
  • Isotype
    IgG2
  • Protein IDP00734
  • Protein Name
    Prothrombin
  • Scientific Description
    Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

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